Cloning and nucleotide sequence of a chromosomally encoded tetracycline resistance determinant, tetA(M), from a pathogenic, methicillin-resistant strain of Staphylococcus aureus

M. Nesin; P. Svec; J. R. Lupski; G. N. Godson; B. Kreiswirth; J. Kornblum; S. J. Projan

doi:10.1128/AAC.34.11.2273

Cloning and nucleotide sequence of a chromosomally encoded tetracycline resistance determinant, tetA(M), from a pathogenic, methicillin-resistant strain of Staphylococcus aureus

M. Nesin
, P. Svec
, J. R. Lupski
, G. N. Godson
, B. Kreiswirth
, J. Kornblum
, S. J. Projan

Public Health Research Institute, New York

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Abstract

This report describes the cloning and sequencing of a chromosomally encoded tetracycline resistance determinant from a clinical isolate of methicillin-resistant Staphylococcus aureus. On the basis of the sequence, the gene is in the tet(M) class, and it was shown that the S. aureus tetA(M) gene is induced at the level of transcription.

Original language	English
Pages (from-to)	2273-2276
Number of pages	4
Journal	Antimicrobial Agents and Chemotherapy
Volume	34
Issue number	11
DOIs	https://doi.org/10.1128/AAC.34.11.2273
State	Published - 1990

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10.1128/AAC.34.11.2273

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Nesin, M., Svec, P., Lupski, J. R., Godson, G. N., Kreiswirth, B., Kornblum, J., & Projan, S. J. (1990). Cloning and nucleotide sequence of a chromosomally encoded tetracycline resistance determinant, tetA(M), from a pathogenic, methicillin-resistant strain of Staphylococcus aureus. Antimicrobial Agents and Chemotherapy, 34(11), 2273-2276. https://doi.org/10.1128/AAC.34.11.2273

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title = "Cloning and nucleotide sequence of a chromosomally encoded tetracycline resistance determinant, tetA(M), from a pathogenic, methicillin-resistant strain of Staphylococcus aureus",

abstract = "This report describes the cloning and sequencing of a chromosomally encoded tetracycline resistance determinant from a clinical isolate of methicillin-resistant Staphylococcus aureus. On the basis of the sequence, the gene is in the tet(M) class, and it was shown that the S. aureus tetA(M) gene is induced at the level of transcription.",

author = "M. Nesin and P. Svec and Lupski, \{J. R.\} and Godson, \{G. N.\} and B. Kreiswirth and J. Kornblum and Projan, \{S. J.\}",

year = "1990",

doi = "10.1128/AAC.34.11.2273",

language = "English",

volume = "34",

pages = "2273--2276",

journal = "Antimicrobial Agents and Chemotherapy",

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publisher = "American Society for Microbiology",

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}

Nesin, M, Svec, P, Lupski, JR, Godson, GN, Kreiswirth, B, Kornblum, J & Projan, SJ 1990, 'Cloning and nucleotide sequence of a chromosomally encoded tetracycline resistance determinant, tetA(M), from a pathogenic, methicillin-resistant strain of Staphylococcus aureus', Antimicrobial Agents and Chemotherapy, vol. 34, no. 11, pp. 2273-2276. https://doi.org/10.1128/AAC.34.11.2273

Cloning and nucleotide sequence of a chromosomally encoded tetracycline resistance determinant, tetA(M), from a pathogenic, methicillin-resistant strain of Staphylococcus aureus. / Nesin, M.; Svec, P.; Lupski, J. R. et al.
In: Antimicrobial Agents and Chemotherapy, Vol. 34, No. 11, 1990, p. 2273-2276.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Cloning and nucleotide sequence of a chromosomally encoded tetracycline resistance determinant, tetA(M), from a pathogenic, methicillin-resistant strain of Staphylococcus aureus

AU - Nesin, M.

AU - Svec, P.

AU - Lupski, J. R.

AU - Godson, G. N.

AU - Kreiswirth, B.

AU - Kornblum, J.

AU - Projan, S. J.

PY - 1990

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AB - This report describes the cloning and sequencing of a chromosomally encoded tetracycline resistance determinant from a clinical isolate of methicillin-resistant Staphylococcus aureus. On the basis of the sequence, the gene is in the tet(M) class, and it was shown that the S. aureus tetA(M) gene is induced at the level of transcription.

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AN - SCOPUS:0025054630

SN - 0066-4804

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EP - 2276

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 11

ER -

Cloning and nucleotide sequence of a chromosomally encoded tetracycline resistance determinant, tetA(M), from a pathogenic, methicillin-resistant strain of Staphylococcus aureus

Abstract

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