Cytogenetics and molecular genetics in multiple myeloma

R. Feinman; J. Sawyer; J. Hardin; G. Tricot

doi:10.1016/S0889-8588(05)70412-3

Cytogenetics and molecular genetics in multiple myeloma

R. Feinman
, J. Sawyer
, J. Hardin
, G. Tricot

Center for Discovery and Innovation

University of Arkansas for Medical Sciences

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

Specific cytogenetic abnormalities have been identified in multiple myeloma that confer a poor prognosis, even with intensive chemotherapy and autotransplants. The identification and characterization of potential genes involved in these different chromosomal changes and their interplay with oncogenes and tumor suppressor genes controlling cellular growth and apoptosis is the major focus of this review.

Original language	English
Pages (from-to)	1-25
Number of pages	25
Journal	Hematology/Oncology Clinics of North America
Volume	11
Issue number	1
DOIs	https://doi.org/10.1016/S0889-8588(05)70412-3
State	Published - 1997

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title = "Cytogenetics and molecular genetics in multiple myeloma",

abstract = "Specific cytogenetic abnormalities have been identified in multiple myeloma that confer a poor prognosis, even with intensive chemotherapy and autotransplants. The identification and characterization of potential genes involved in these different chromosomal changes and their interplay with oncogenes and tumor suppressor genes controlling cellular growth and apoptosis is the major focus of this review.",

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AU - Feinman, R.

AU - Sawyer, J.

AU - Hardin, J.

AU - Tricot, G.

PY - 1997

Y1 - 1997

N2 - Specific cytogenetic abnormalities have been identified in multiple myeloma that confer a poor prognosis, even with intensive chemotherapy and autotransplants. The identification and characterization of potential genes involved in these different chromosomal changes and their interplay with oncogenes and tumor suppressor genes controlling cellular growth and apoptosis is the major focus of this review.

AB - Specific cytogenetic abnormalities have been identified in multiple myeloma that confer a poor prognosis, even with intensive chemotherapy and autotransplants. The identification and characterization of potential genes involved in these different chromosomal changes and their interplay with oncogenes and tumor suppressor genes controlling cellular growth and apoptosis is the major focus of this review.

UR - https://www.scopus.com/pages/publications/0030991361

U2 - 10.1016/S0889-8588(05)70412-3

DO - 10.1016/S0889-8588(05)70412-3

M3 - Article

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AN - SCOPUS:0030991361

SN - 0889-8588

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JO - Hematology/Oncology Clinics of North America

JF - Hematology/Oncology Clinics of North America

IS - 1

ER -

Cytogenetics and molecular genetics in multiple myeloma

Abstract

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