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EXPERIMENTAL DESIGN CONSIDERATIONS IN PHARMACOKINETIC STUDIES

  • National Institutes of Health

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Pharmacokinetic studies are conducted in experimental contexts to define pharmacokinetic relationships for new drugs that may be beneficial for patients and to enable the understanding the concentration-effect relationships. For both these purposes, an accurate description of pharmacokinetics is vital, which can be achieved by appropriate experimental design. This article describes some of the issues in the design of experimental models, which enable pharmacokinetic relationships to be established.

Original languageEnglish
Title of host publicationPharmaceutical Sciences Encyclopedia
Publisherwiley
Pages1-10
Number of pages10
ISBN (Electronic)9780470571224
DOIs
StatePublished - 1 Jan 2010

Keywords

  • experimental design
  • experimental models
  • pharmacokinetic studies
  • sampling time

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