Immune mechanisms in neoplasia

Chiara Castelli; Piero Dalerba; Chiara Casati; Luisa Novellino; Giorgio Parmiani; Annamaria De Filippo

doi:10.1016/j.ddmec.2004.11.007

Immune mechanisms in neoplasia

Chiara Castelli
, Piero Dalerba
, Chiara Casati
, Luisa Novellino
, Giorgio Parmiani
, Annamaria De Filippo

Center for Discovery and Innovation

IRCCS Fondazione Istituto Nazionale per lo studio e la cura dei tumori - Milano

Research output: Contribution to journal › Review article › peer-review

Abstract

Tumor can be recognized by the immune system the witnessed extraordinary advances in our understanding of tumor-host interactions. Here, we review evidence supporting the double role of the adaptive immune system in exerting both host-protecting tumor-shaping actions. We will then some of the molecular mechanisms of the adaptive immune response tumor to grow in an immonocompetent host, along with strategies that can potentially overcome the ability of the tumor to evade the immune system.

Original language	English
Pages (from-to)	375-381
Number of pages	7
Journal	Drug Discovery Today: Disease Mechanisms
Volume	1
Issue number	3
DOIs	https://doi.org/10.1016/j.ddmec.2004.11.007
State	Published - Dec 2004

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10.1016/j.ddmec.2004.11.007

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title = "Immune mechanisms in neoplasia",

abstract = "Tumor can be recognized by the immune system the witnessed extraordinary advances in our understanding of tumor-host interactions. Here, we review evidence supporting the double role of the adaptive immune system in exerting both host-protecting tumor-shaping actions. We will then some of the molecular mechanisms of the adaptive immune response tumor to grow in an immonocompetent host, along with strategies that can potentially overcome the ability of the tumor to evade the immune system.",

author = "Chiara Castelli and Piero Dalerba and Chiara Casati and Luisa Novellino and Giorgio Parmiani and \{De Filippo\}, Annamaria",

year = "2004",

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T1 - Immune mechanisms in neoplasia

AU - Castelli, Chiara

AU - Dalerba, Piero

AU - Casati, Chiara

AU - Novellino, Luisa

AU - Parmiani, Giorgio

AU - De Filippo, Annamaria

PY - 2004/12

Y1 - 2004/12

N2 - Tumor can be recognized by the immune system the witnessed extraordinary advances in our understanding of tumor-host interactions. Here, we review evidence supporting the double role of the adaptive immune system in exerting both host-protecting tumor-shaping actions. We will then some of the molecular mechanisms of the adaptive immune response tumor to grow in an immonocompetent host, along with strategies that can potentially overcome the ability of the tumor to evade the immune system.

AB - Tumor can be recognized by the immune system the witnessed extraordinary advances in our understanding of tumor-host interactions. Here, we review evidence supporting the double role of the adaptive immune system in exerting both host-protecting tumor-shaping actions. We will then some of the molecular mechanisms of the adaptive immune response tumor to grow in an immonocompetent host, along with strategies that can potentially overcome the ability of the tumor to evade the immune system.

UR - https://www.scopus.com/pages/publications/23744467432

U2 - 10.1016/j.ddmec.2004.11.007

DO - 10.1016/j.ddmec.2004.11.007

M3 - Review article

AN - SCOPUS:23744467432

SN - 1740-6765

VL - 1

SP - 375

EP - 381

JO - Drug Discovery Today: Disease Mechanisms

JF - Drug Discovery Today: Disease Mechanisms

IS - 3

ER -

Immune mechanisms in neoplasia

Abstract

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