Treatment of acute delirium in a patient with parkinson’s disease by transfer to the intensive care unit and administration of dexmedetomidine

Morgan Lombardo; Amanda Dipiazza; Kelly Rippey; Naomi Lubarr; Elana Clar; Hooman Azmi

doi:10.14802/jmd.20005

Treatment of acute delirium in a patient with parkinson’s disease by transfer to the intensive care unit and administration of dexmedetomidine

Morgan Lombardo
, Amanda Dipiazza
, Kelly Rippey
, Naomi Lubarr
, Elana Clar
, Hooman Azmi

School of Medicine

Rutgers - The State University of New Jersey, Newark
North Jersey Brain and Spine Center

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The treatment of delirium or psychosis in patients with Parkinson’s disease (PD) can be complicated by the limited number of pharmacological agents that can be used in this population. Typical and atypical antipsychotics are contraindicated, as they can worsen motor symptoms. The treatment of acute delirium is even more complicated in the hospital setting, as many medications deemed safer in this population are only available in oral form. We present a case of acute delirium in a patient with PD, likely precipitated by a polypharmacy interaction of new medications, that was successfully managed by transferring the patient to the intensive care unit and administering dexmedetomidine for 72 hours.

Original language	English
Pages (from-to)	159-162
Number of pages	4
Journal	Journal of Movement Disorders
Volume	13
Issue number	2
DOIs	https://doi.org/10.14802/jmd.20005
State	Published - May 2020

Keywords

AaDelirium
Dexmedetomidine
Parkinson’s disease
Treatment

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10.14802/jmd.20005

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title = "Treatment of acute delirium in a patient with parkinson{\textquoteright}s disease by transfer to the intensive care unit and administration of dexmedetomidine",

abstract = "The treatment of delirium or psychosis in patients with Parkinson{\textquoteright}s disease (PD) can be complicated by the limited number of pharmacological agents that can be used in this population. Typical and atypical antipsychotics are contraindicated, as they can worsen motor symptoms. The treatment of acute delirium is even more complicated in the hospital setting, as many medications deemed safer in this population are only available in oral form. We present a case of acute delirium in a patient with PD, likely precipitated by a polypharmacy interaction of new medications, that was successfully managed by transferring the patient to the intensive care unit and administering dexmedetomidine for 72 hours.",

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AU - Dipiazza, Amanda

AU - Rippey, Kelly

AU - Lubarr, Naomi

AU - Clar, Elana

AU - Azmi, Hooman

PY - 2020/5

Y1 - 2020/5

N2 - The treatment of delirium or psychosis in patients with Parkinson’s disease (PD) can be complicated by the limited number of pharmacological agents that can be used in this population. Typical and atypical antipsychotics are contraindicated, as they can worsen motor symptoms. The treatment of acute delirium is even more complicated in the hospital setting, as many medications deemed safer in this population are only available in oral form. We present a case of acute delirium in a patient with PD, likely precipitated by a polypharmacy interaction of new medications, that was successfully managed by transferring the patient to the intensive care unit and administering dexmedetomidine for 72 hours.

AB - The treatment of delirium or psychosis in patients with Parkinson’s disease (PD) can be complicated by the limited number of pharmacological agents that can be used in this population. Typical and atypical antipsychotics are contraindicated, as they can worsen motor symptoms. The treatment of acute delirium is even more complicated in the hospital setting, as many medications deemed safer in this population are only available in oral form. We present a case of acute delirium in a patient with PD, likely precipitated by a polypharmacy interaction of new medications, that was successfully managed by transferring the patient to the intensive care unit and administering dexmedetomidine for 72 hours.

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KW - Parkinson’s disease

KW - Treatment

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JF - Journal of Movement Disorders

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ER -

Treatment of acute delirium in a patient with parkinson’s disease by transfer to the intensive care unit and administration of dexmedetomidine

Abstract

Keywords

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